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Laura V Bownes Selected Research

Messenger RNA (mRNA)

1/2022CRISPR/Cas9-mediated knockout of PIM3 suppresses tumorigenesis and cancer cell stemness in human hepatoblastoma cells.
6/2021Novel second-generation rexinoid induces growth arrest and reduces cancer cell stemness in human neuroblastoma patient-derived xenografts.
1/20219-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts.

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Laura V Bownes Research Topics

Disease

13Neoplasms (Cancer)
06/2023 - 06/2020
10Neuroblastoma
03/2024 - 06/2020
6Hepatoblastoma
06/2023 - 01/2021
5Carcinogenesis
06/2023 - 01/2021
1Sarcoma (Soft Tissue Sarcoma)
10/2023
1Hypoxia (Hypoxemia)
01/2023
1Neoplasm Metastasis (Metastasis)
12/2022

Drug/Important Bio-Agent (IBA)

5proto-oncogene proteins pimIBA
03/2024 - 01/2021
4Phosphotransferases (Kinase)IBA
03/2024 - 01/2022
3Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
03/2024 - 06/2021
3Cisplatin (Platino)FDA LinkGeneric
06/2022 - 01/2021
3Messenger RNA (mRNA)IBA
01/2022 - 01/2021
3Tretinoin (Retinoic Acid)FDA LinkGeneric
06/2021 - 06/2020
2AZD1208IBA
03/2024 - 01/2021
2Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
06/2023 - 04/2022
2Proteins (Proteins, Gene)FDA Link
06/2022 - 06/2021
2UAB 30IBA
01/2021 - 06/2020
1multidrug resistance-associated protein 1IBA
03/2024
1Doxorubicin (Adriamycin)FDA LinkGeneric
03/2024
1Retinoblastoma ProteinIBA
10/2023
1SulfonamidesIBA
06/2023
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
06/2023
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
06/2023
1AlginatesIBA
01/2023
1GelatinIBA
01/2023
1plerixaforFDA Link
12/2022
1Chemokine ReceptorsIBA
12/2022
1Focal Adhesion Protein-Tyrosine KinasesIBA
06/2022
16- (4- (3- (methylsulfonyl)benzylamino)- 5- (trifluoromethyl)pyrimidin- 2- ylamino)- 3,4- dihydroquinolin- 2(1H)- oneIBA
06/2022
1Fingolimod Hydrochloride (FTY720)FDA Link
04/2022
1CrizotinibIBA
07/2021
1Sunitinib (Sutent)FDA Link
07/2021
1Strap proteinIBA
06/2021
1Small Interfering RNA (siRNA)IBA
06/2021
1Enhancer of Zeste Homolog 2 ProteinIBA
01/2021
1GSK343IBA
01/2021

Therapy/Procedure

8Therapeutics
06/2023 - 06/2020
1Injections
06/2022
1Oncolytic Virotherapy
02/2022
1Drug Therapy (Chemotherapy)
01/2021